NAD⁺ and Wellbeing: What It Is, Why It Matters, and How People Are Using It
NAD⁺ and Wellbeing: What It Is, Why It Matters, and How People Are Using It
In the ever-evolving wellness landscape, some trends come and go — while others quietly earn their place through science, consistency, and real-world results. NAD⁺ (nicotinamide adenine dinucleotide) sits firmly in the latter category.
Rather than a quick fix or beauty buzzword, NAD⁺ is a naturally occurring coenzyme found in every cell of the body. It plays a fundamental role in how we create energy, repair cellular damage, and maintain balance as we age. As NAD⁺ levels naturally decline over time, interest has grown around ways to support and replenish it — not for longevity hype, but for everyday wellbeing.
Why NAD⁺ Matters for How You Feel
At its core, NAD⁺ supports some of the most essential processes in the body:
Cellular energy production — helping convert food into usable energy
DNA repair and cellular resilience — supporting the body’s natural repair systems
Nervous system function — influencing fatigue, mental clarity, and stress response
Metabolic health — playing a role in how efficiently the body functions overall
Research consistently shows that maintaining healthy NAD⁺ levels is associated with improved cellular function, which can translate into feeling more energised, clearer, and resilient — especially during periods of physical or emotional demand.
Rather than “doing more,” NAD⁺ support is often about helping the body do what it already knows how to do — more efficiently.
How People Are Supporting Their NAD⁺ Levels
There are several ways people choose to support NAD⁺ as part of their wellness routine. Each approach reflects different needs, lifestyles, and levels of clinical support.
1. Oral Supplementation
Many people choose oral NAD⁺ support via precursors such as NMN or NR, which the body can convert into NAD⁺. These options are widely researched, accessible, and often used as part of a daily wellness routine focused on energy, recovery, and longevity support.
2. Liposomal Formulations
Liposomal supplements are designed to enhance absorption by protecting nutrients as they move through the digestive system. While liposomal delivery shows promise for some nutrients, current research on liposomal NAD⁺ itself is still emerging. As with all supplements, quality, formulation, and evidence matter.
3. Injectable or IV NAD⁺
Some individuals explore NAD⁺ via injectable or IV delivery under medical supervision. This approach is typically used in clinical or integrative health settings and may be chosen by those seeking more immediate support during periods of burnout, fatigue, or high stress. As with any medical intervention, professional guidance is essential.
Importantly, no single method is “best” for everyone. Wellness is personal — and effective care meets the body where it is.
NAD⁺ as Part of a Holistic Wellness Approach
What’s often missing from conversations around NAD⁺ is context. NAD⁺ doesn’t work in isolation — and it’s not a substitute for rest, nourishment, movement, or nervous system care.
Its real value lies in supporting the foundations of wellbeing, particularly when paired with:
Quality sleep and recovery
Gentle, consistent movement
Stress regulation and nervous system support
Thoughtful, evidence-based self-care
In this way, NAD⁺ becomes less about “optimisation” and more about restoration — helping the body feel supported rather than pushed.
A Grounded Perspective
While research continues to evolve, current human studies support NAD⁺-related therapies as generally safe when used appropriately, with growing evidence for their role in cellular health and energy regulation. As always, individual needs vary, and it’s wise to seek professional guidance — particularly when exploring higher-dose or injectable options.
At MO+, we view wellness tools like NAD⁺ not as silver bullets, but as part of a broader conversation about how we care for ourselves in busy, demanding lives.
Sometimes wellbeing isn’t about adding more — it’s about choosing support that helps you feel like yourself again.
Where People Access NAD⁺ Support
NAD⁺ is available in several formats, and where you purchase it matters. Quality, sourcing, and medical oversight are essential — particularly for higher-dose or injectable options.
Injectable / IV NAD⁺
NAD⁺ injections and IV infusions are typically accessed through:
Integrative medical clinics
Longevity or metabolic health clinics
Functional medicine practitioners
GP-led wellness or regenerative health practices
These services are provided under medical supervision and usually require a consultation to assess suitability, dosing, and goals.
Capsules & Liposomal Supplements
Oral NAD⁺ support (often via precursors such as NMN or NR, or liposomal formulations) can be purchased through:
Practitioner-only supplement dispensaries
Reputable wellness clinics
Evidence-based supplement brands with third-party testing
When choosing oral supplements, look for:
Transparent sourcing and clinical-grade manufacturing
Clear lab testing and dosage information
Brands that reference human research, not just marketing claims
As always, NAD⁺ support is best approached as part of a broader wellbeing plan and, where possible, guided by a qualified health professional.
NAD⁺ vs NMN: What’s the Difference?
While NAD⁺ often gets the spotlight, it’s important to understand the difference between NAD⁺ itself and NMN (nicotinamide mononucleotide) — one of its most well-researched precursors.
NAD⁺ is the active coenzyme used directly inside cells to support energy production, DNA repair and cellular resilience. Because it’s a large and relatively unstable molecule, the body doesn’t easily absorb NAD⁺ intact — which is why injectable or IV forms are typically offered under medical supervision.
NMN, on the other hand, is a smaller precursor molecule that the body can convert into NAD⁺ through natural metabolic pathways. Human clinical studies show that oral NMN supplementation can safely increase blood NAD⁺ levels, making it a popular option for those seeking daily, non-invasive support.
In simple terms:
NAD⁺ = the active molecule your cells use
NMN = a building block your body converts into NAD⁺
Both approaches aim to support the same underlying goal — healthy cellular NAD⁺ levels — but they differ in delivery, intensity and accessibility.
Cost Considerations: NAD⁺ vs NMN vs NAD⁺ Capsules
Cost is often a deciding factor when choosing how to support NAD⁺ levels, alongside accessibility, intensity, and how the support fits into daily life.
Injectable or IV NAD⁺
Typically accessed through medical or integrative clinics
Usually requires an initial consultation and clinical oversight
Costs can range from several hundred dollars per session, depending on dose and delivery method
Often used periodically rather than daily (e.g. during high stress, fatigue, or burnout phases)
NAD⁺ Capsules (Oral NAD⁺)
Purchased as capsules through wellness clinics or supplement providers
Designed for ongoing, daily use
Monthly costs generally sit below injectable options, but often above NMN, depending on brand and formulation
Convenience is high, though evidence suggests the body may need to break NAD⁺ down into smaller components before use
NMN (Oral Supplementation)
Purchased as capsules or powder
Designed for daily, long-term support
Monthly costs generally sit significantly lower than injectable options, depending on brand and dosage
Supported by multiple human safety and efficacy studies showing increases in blood NAD⁺ levels
A Balanced Perspective
At MO+, we view both NAD⁺ and NMN as supportive tools, not magic solutions. The most meaningful results come when cellular support is paired with rest, nervous system regulation, movement and intentional recovery.
Wellbeing isn’t about choosing the most extreme option — it’s about choosing what’s appropriate, sustainable and aligned with your life.